Glaucoma Technologies Enrolling Centers Publications
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Journal Articles
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Peer-Reviewed Journal Articles



Huang, X-R and Knighton, RW. Microtubules contribute to the birefringence of the retinal nerve fiber layer. Invest Ophthalmol Vis Sci 2005; 46:4588-4593.
Sehi M, Greenfield DS. Assessment of retinal nerve fiber layer using optical coherence tomography and scanning laser polarimetry in progressive glaucomatous optic neuropathy. Am J Ophthalmol 2005; 142:1056-1059.




Sarunic MV, Applegate BE, Izatt JA, Real time quadrature projection complex conjugate resolved Fourier domain optical coherence tomography. Optics Letters 2006; 31(16):2426-2428.
XR Huang, RW Knighton, V Shestopalov. Quantifying retinal nerve fiber layer thickness in whole-mounted retina. Experimental Eye Research 2006; 83:1096-1101
SR Sadda, O Tan, AC Walsh, JS Schuman, R Varma, D Huang Automated Detection of Clinically Significant Macular Edema by Grid Scanning Optical Coherence Tomography. Ophthalmology 2006; 113(7):1187.e1-1187.12




Memarzadeh F, Li Y, Chopra V, Varma R, Francis B, Huang D Anterior segment optical coherence tomography for imaging the anterior chamber following laser peripheral iridotomy. Am J Ophthalmol 2007; 143:887-879.
Pedersen CJ, Huang D, Shure MA, Rollins AM. Measurement of absolute flow velocity vector using dual-angle delay-encoded Doppler optical coherence tomography. Optics Letters 2007; 32(5):506-508
Sehi M, Guaqueta DC, Feuer WJ, Greenfield DS, Advanced imaging in glaucoma study group. Scanning laser polarimetry with variable and enhanced corneal compensation in normal and glaucomatous eyes. Am J Ophthalmol 2007; 143(2):272-279.
Sehi M, Ume S, Greenfield D, Advanced Imaging in Glaucoma Study Group. Scanning Laser Polarimetry with Enhanced Corneal Compensation and Optical Coherence Tomography in Normal and Glaucomatous Eyes. Invest Ophthalmol Vis Sci. 2007; 48:2099-2102.
Wang Y, Bower BA, Izatt JA, Tan O, Huang D. In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography. Journal of Biomedical Optics, 2007; 12:041215-22.
Memarzadeh F, Tang M, Li Y, Chopra V, Francis BA, Huang D. Optical Coherence Tomography Assessment of Angle Anatomy Changes after Cataract Surgery, Am J Ophthalmol 2007; 144:464-465.




Asrani, S, Sarunic, M, Santiago, C, Izatt, J Detailed Visualization of the Anterior Segment Using Fourier-Domain Optical Coherence Tomography. Arch Ophthalmol 2008; 126(6):765-771.
Lu,A, Wang,M, Varma,R, Schuman,J, Greenfield,D, Smith,S, Huang,D, AIGS Combining Nerve Finger Layer to Optimize Glaucoma Diagnosis with Optical Coherence Tomography. Ophthalmology 2008; 115(8):1352-1357.e2.
Asrani, S, Sarunic, M, Santiago, C, Izatt, J Detailed Visualization of the Anterior Segment Using Fourier-Domain Optical Coherence Tomography.. Arch Ophthalmol. 2008; 126(6):765-771.
Alasil, T, Tan, O, Lu A, Huang D, Sadun A A Correlation of Fourier Domain Optical Coherence Tomography Retinal Nerve Fiber Layer Maps With Visual Fields in Nonarteritic Ischemic Optic Neuropathy. Ophthalmic Surg Lasers Imaging 2008; 39(4 Suppl):S71-S79.
Mumcuoglu T, Townsend KA, Wollstein G, Ishikawa H, Bilonick RA, Sung KR, Kagemann L, Schuman JS Manuscript #AJO-08-106. Am J Ophthalmol Accepted for Publication: May 28, 2008.
Greenfield DS, Weinreb RN. Role of optic nerve imaging in glaucoma clinical practice and clinical trials. Am J Ophthalmol 2008; 145:598-603.
Tan O, Li Gisele, Lu AT-H, Varma R, Advanced Imaging for Glaucoma Study Group, Huang D. Mapping of Macular Substructures with Optical Coherence Tomography for Glaucoma Diagnosis. Ophthalmology 2008; 115:949-56.




Mingtao Zhao* and Joseph A. Izatt Single-camera Sequential-scan-based Polarization-sensitive SDOCT For Retinal Imaging. Spectral-domain optical-coherence tomography 2009; 34(2):205207.
Y Wang, A Lu, J Gil-Flamer, O Tan, J A Izatt, and D Huang. Measurement of total blood flow in the normal human retina using Doppler Fourier-domain optical coherence tomography, Br J Ophthalmol. 2009; 93(5):634637.
Sung KR, Wollstein G, Bilonick RA, Ishikawa H, Towsend KA, Kagemann L, Gabriele ML, Advanced Imaging in Glaucoma Study Group, Schuman JS. Scan quality affects glaucoma discrimination by glaucoma imaging devices. Br J Ophthalmol. 2009; 93:1580-1584.
Tan O, Chopra V, Lu ATH, Schuman JS, Ishikawa H, Wollstein G, Varma R, Huang D. Detection of macular ganglion cell loss in glaucoma by Fourier-domain optical coherence tomography. Ophthalmology 2009; 116:2305-2314.




Grzywacz NM, de Juan J, Cluaida F, Giannini D, Huang D, Koch G, Russo V, Tan O, Bruni C. Statistics of optical coherence tomography data from human retina. IEEE Transactions on Medical Imaging 2010; 29:1224-1237.
Potsaid B, Baumann B, Huang D, Barry S, Schuman JS, Duker JS, Fujimoto JG. Ultrahigh speed 1050nm swept-source/Fourier domain OCT retinal and anterior segment imaging at 100,000 to 400,000 axial scans per second. Optics Express 2010; 18(19):20029-20048.
Ho J, Castro DP, Castro LC, Chen Y, Liu J, Mattox C, Krishnan C, Fujimoto JG, Schuman JS, Duker JS. Clinical assessment of mirror artifacts in spectral domain optical coherence tomography. Invest Ophthalmol Vis Sci 2010;51:3714-3720. PMCID: PMC2904018
Manjunath V, Taha M, Fujimoto JG, Duker JS. Choroidal thickness in normal eyes measured using Cirrus HD optical coherence tomography. Am J Ophthalmol 2010;150:325-329. PMCID: PMC2926223




Wang Y, Fawzi AA, Varma R, Sadun AA, Zhang X, Tan O, Izatt JA, Huang D. Pilot study of optical coherence tomography measurement of retinal blood flow in retinal and optic nerve diseases. Invest Ophthalmol Vis Sci 2011;52:840-845. PMCID: PMC3053109
Manjunath V, Taha M, Fujimoto JG, Duker JS. Posterior lattice degeneration characterized by spectral domain optical coherence tomography. Retina 2011;31:492-496. PMCID: PMC3058864
Manjuanth V, Shah H, Fujimoto JG, Duker JS. Analysis of peripapillary atrophy using spectral domain optical coherence tomography. Ophthalmol 2011;118:531-536. PMCID: PMC3017221
Ho J, Witkin AJ, Liu J, Chen Y, Fujimoto JG, Schuman JS. Documentation of intraretinal pigment epithelium migration via high-speed ultrahigh-resolution optical coherence tomography. Ophthalmol 2011;118:687-693. PMCID: PMC3070873
Baumann B, Potsaid B, Liu JJ, Kraus MF, Huang D, Hornegger J, Duker JS, Fujimoto JG. Total retinal blood flow measurement with ultrahigh speed swept source/Fourier domain OCT. Biomedical Optics Express 2011; 2(6):1539-1552.
Grewal DS, Sehi M, Greenfield DS. Detecting glaucomatous progression using GDx with variable and enhanced corneal compensation using Guided Progression Analysis. Br J Ophthalmol 2011;95:502-508. PMID20650911




Baumann B, Choi W, Potsaid B, Huang D, Duker JS, Fujimoto JG. Swept source/Fourier domain polarization sensitive optical coherence tomography with a passive polarization delay unit. Opt Express. Apr 23 2012;20(9):10218-10230. PMCID:PMC3366588
Hwang JC, Konduru R, Zhang X, Tan O, Francis BA, Varma R, Sehi M, Greenfield DS, Sadda SR, Huang D. Relationship among visual field, blood flow, and neural structure measurements in glaucoma. Invest Ophthalmol Vis Sci. 2012: 17; 53(6):3020-6. PMCID: PMC3378085.
Jia Y, Tan O, Tokayer J, Potsaid BM, Wang Y, Liu JJ, Kraus MF, Subhash H, Fujimoto JG, Hornegger J, Huang D. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Opt Express 2012;20:4710-4725. PMCID: PMC3381646.
Folio LS, Wollstein G, Ishikawa H, Bilonick RA, Ling Y, Kagemann L, Noecker RJ, Fujimoto JG, Duker JS, Schuman JS. Variation in Optical Coherence Tomography Signal Quality as an Indicator of Retinal Nerve Fiber Layer Segmentation Error. Br J Ophthalmol 2012; 96: 514-8.PMCID: PMC3375178.
Ungar AK, Wollstein G, Ishikawa H, Folio LS, Ling Y, Bilonick RA, Noecker RJ, Xu J, Kagemann L, Mattox C, Schuman JS. Evaluating Objective and Subjective Quantitative Parameters at the Initial Visit to Predict Future Glaucomatous Visual Field Progression. Ophthal Surg Las Imag 2012; 31: 1-9. PMCID: PMC3444548.
Nadler Z, Wollstein G, Ishikawa H, Schuman JS. Clinical Application of Ocular Imaging. Opt Vis Sci 2012; 89: 543-53. PMCID: PMC3348430.
Wang Y, Fawzi AA, Tan O, Zhang, X, Huang D. Flicker-induced changes in retinal blood flow assessed by doppler optical coherence tomography. Biomed Opt Express 2011;2:1852-1860. PMCID: PMC3130572.
Bujak MC, Yiu S, Zhang X, Li Y, Huang D. Serial measurement of tear meniscus by FD-OCT after instillation of artificial tears in patients with dry eyes. Ophthalmic Surgery, Lasers & Imaging 2011;42:308-313. PMC Journal In Process.
Tittler EH, Bujak MC, Nguyen P, Zhang X, Li Y, Yiu SC, Huang D. Between-grader repeatability of tear meniscus measurements using fourier-domain optical coherence tomography in patients with dry eye. Ophthalmic Surg Lasers & Imaging 2011;42:423-427. PMC Journal In Process.
Konduru R, Tan O, Nittala MG, Huang D, Sadda SR. Reproducibility of retinal blood flow measurements derived from semi-automated Doppler OCT analysis. Ophthalmic Surg Lasers and Imaging 2012;43:25-31. PMC Journal In Process.




Tokayer J, Jia Y, Dhalla AH, Huang D. Blood flow velocity quantification using split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Biomedical Opt Express 2013;4:1909-1924. PMCID: PMC3799655.
Lee JC, Wong B, Tan O, Srinivas S, Sadda SR, Huang D, Fawzi AA. Pilot study of Doppler optical coherence tomography of retinal blood flow following laser photocoagulation in poorly controlled diabetic patients. Invest Ophthalmol Vis Sci 2013;54:6104-6111. PMCID: PMC3771559.
Hwang JC, Khine KT, Rao NA, Minckler DS, Memarzadeh F, Li Y, Huang D, Francis BA. Assessment of the anterior chamber angle after trabectome glaucoma surgery by optical coherence tomography, histopathology, ultrasound biomicroscopy and scanning electron microscopy. Int J Ophthalmic Pathol 2013 2:4.
Wei E, Jia Y, Tan O, Potsaid B, Liu JJ, Choi WJ, Fujimoto JG, Huang D. Parafoveal retinal vascular response to pattern visual stimulation assessed with OCT angiography. PLoS ONE 8(12): e81343. Doi:10.1371/journal.pone.0081343.




Sehi M, Goharian I, Konduru R, Tan O, Srinivas S, Sadda, SR, Francis BA, Huang D, Greenfield DS. Retinal blood flow in glaucomatous eyes with single-hemifield damage. Ophthal 2014;121:750-758. doi: 10.1016/j.ophtha.2013.10.022. PMCID: PMC3943621.
Jia Y, Wei E, Wang X, Zhang X, Morricson JC, Parikh M, Lombardi LH, Gattey DM, Armour RL, Edmunds B, Kraus MF, Fujimoto JG, Huang D. Optical coherence tomography angiography of optic disc perfusion in glaucoma. Ophthal 2014;121:1322-1332. PMCID: PMC4082728.
Le PV, Zhang X, Francis BA, Varma R, Greenfield DS, Schuman JS, Loewen N, Huang D, Advanced Imaging for Glaucoma Study Group. Advanced imaging for glaucoma study: design, baseline characteristics and inter-site comparison. . Am J Ophthal 2014. PMCID: PMC4277893.
Loewen NA, Zhang X, Tan O, Frnacis BA, Greenfield DS, Schuman JS, Varma R, Huang D. Combining measurements from three anatomical areas for glaucoma diagnosis using Fourier-domain optical coherence tomography. . Br J Ophthalmol doi:10.1136/bjophthalmol-2014-305907. PMC Journal In Process.